Most men who search for the P-Shot have already done some reading. They know it involves platelet-rich plasma. They know it is non-surgical. What they are less sure about is whether it is clinically credible, whether it is right for them, and what an actual consultation and treatment experience looks like at a reputable London clinic. This guide answers those questions directly. The P-Shot, formally known as the Priapus Shot, is a procedure in which platelet-rich plasma derived from the patient’s own blood is injected into specific areas of the penis to support tissue health, vascular function, and sexual performance. At Dr SW Clinics on Harley Street, London, it is offered as part of a clinically assessed, individually tailored approach to male sexual wellness, not as a standalone product sold on the promise of dramatic results.
The P-Shot was developed by American physician Dr Charles Runels and is based on the broader application of platelet-rich plasma therapy, which has been used in orthopaedics, wound healing, and dermatology for several decades. The principle is consistent across applications: by concentrating the growth factors naturally present in blood platelets and delivering them directly to target tissue, PRP is intended to stimulate cellular repair, improve blood supply, and support regeneration.
In the context of male sexual health, the areas targeted include the penile shaft and the area around the base of the penis. The growth factors delivered are thought to support the health of smooth muscle tissue and blood vessels that are fundamental to erectile function.
The procedure is not classified as a pharmaceutical treatment and is not regulated by the MHRA as a drug. It is a medical procedure that requires clinical training and appropriate patient selection to be used responsibly.
At Dr SW Clinics, the P-Shot is considered as part of the clinical assessment for men presenting with:
It is important to state clearly that the P-Shot is not a cure for erectile dysfunction and is not appropriate as a standalone treatment where significant vascular disease, neurological damage, or hormonal deficiency is the primary cause. Clinical assessment determines appropriateness, not the patient’s wish for a particular treatment.
At Dr SW Clinics, this assessment falls within the clinic’s established framework for sexual rejuvenation, treating male and female intimate health with the same clinical rigour applied to any other area of medicine.
Understanding exactly what happens during a P-Shot appointment removes a significant amount of anxiety for men considering the treatment. Here is what the process involves at Dr SW Clinics:
Step 1: Consultation and assessment Dr Sherif Wakil conducts a thorough medical and sexual health history. The purpose, likely outcomes, alternatives, and risks of PRP therapy are discussed in full. No treatment is agreed without informed consent.
Step 2: Blood draw A small volume of blood, typically 20 to 60 millilitres, is drawn from the patient’s arm in the same way as a standard blood test.
Step 3: Centrifugation The blood sample is placed in a centrifuge, which spins it at high speed to separate the platelet-rich plasma from other blood components. This takes approximately 10 minutes.
Step 4: Topical anaesthesia A topical anaesthetic cream is applied to the penis and allowed to take effect before any injections are administered. Patient comfort is a clinical priority, not an afterthought.
Step 5: PRP injection The concentrated PRP is injected into specific areas using a fine needle. The procedure is performed with precision to target the tissue most likely to benefit.
Step 6: Aftercare Patients receive written aftercare instructions. Most men experience minimal downtime, though some temporary swelling or bruising may occur. A follow-up appointment is arranged to assess response.
The evidence base for PRP in erectile dysfunction is still developing. It is growing, but it is not yet at the level where major clinical bodies have endorsed it as a first-line treatment. Here is an honest summary of where the science currently sits:
The honest clinical position is that PRP for ED shows meaningful promise, particularly for men with mild to moderate vasculogenic or age-related dysfunction, and has a low risk profile given that it uses the patient’s own biological material. It is not a proven cure, and responsible clinicians present it on that basis.
There are several providers in London offering PRP-based treatments for men. The relevant questions are not who offers it, but who assesses properly before offering it, who delivers it in a genuinely clinical environment, and who provides honest information about what it can and cannot achieve.
Dr Sherif Wakil’s background in sexual wellness medicine means that the P-Shot at Dr SW Clinics is embedded within a broader clinical picture, not sold as a single-session solution. International patients travel to the Harley Street clinic specifically for his expertise in this field. The clinic’s approach to male intimate health reflects the principles set out in The O Concept, a philosophy that integrates sexual wellness with physical and psychological health rather than treating it as a cosmetic add-on.
For men managing broader health alongside sexual concerns, the clinic’s life optimisation programmes provide a structured framework for addressing hormonal, metabolic, and sexual health concurrently.
All consultations are conducted in a private setting. Records are handled in full compliance with UK GDPR. Enquiries are welcomed from men at any stage of their decision-making process.
Book a confidential consultation at Dr SW Clinics to discuss whether the P-Shot is clinically appropriate for you.
A topical anaesthetic is applied before the procedure, and most patients report the experience as tolerable. Some mild discomfort, temporary swelling, or sensitivity may occur in the days following treatment.
This depends on the individual and the condition being addressed. Some men benefit from a single treatment, while others may be advised to consider a repeat session after an appropriate interval. Your clinician will discuss this at consultation.
Some men report changes within a few weeks of treatment. For others, the process of tissue regeneration means that results become more apparent over 2 to 3 months. Results are not immediate in the way that oral medication is.
Because PRP is derived from the patient’s own blood, the risk of allergic reaction or immune response is negligible. The primary risks are those associated with injection itself, including bruising and temporary discomfort. Serious adverse events are rare.
In appropriate cases, yes. PRP may be used alongside shockwave therapy, hormone optimisation, or lifestyle intervention as part of a comprehensive treatment plan. This is determined individually at consultation.
The P-Shot is not currently available through NHS pathways. It is offered at specialist private clinics including Dr SW Clinics on Harley Street.
Dr SW Clinics
We offer 0% finance on all our treatments, please call the clinic to find out more +44 (0)20 3006 8459